Louis R Pasquale Selected Research

Exfoliation Syndrome

1/2021	Association of Rare CYP39A1 Variants With Exfoliation Syndrome Involving the Anterior Chamber of the Eye.
1/2018	LOXL1 Polymorphisms: Genetic Biomarkers that Presage Environmental Determinants of Exfoliation Syndrome.
1/2018	A Role for Clusterin in Exfoliation Syndrome and Exfoliation Glaucoma?
1/2017	Genetics of glaucoma.
9/2016	Contribution of the Nurses' Health Study to the Epidemiology of Cataract, Age-Related Macular Degeneration, and Glaucoma.
10/2015	Association of clusterin (CLU) variants and exfoliation syndrome: An analysis in two Caucasian studies and a meta-analysis.
10/2014	Exfoliation syndrome in sub-Saharan Africa.
10/2014	Prospects for gene-environment interactions in exfoliation syndrome.
10/2014	Expression and regulation of LOXL1 and elastin-related genes in eyes with exfoliation syndrome.
5/2014	A prospective study of folate, vitamin B₆, and vitamin B₁₂ intake in relation to exfoliation glaucoma or suspected exfoliation glaucoma.

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Louis R Pasquale Research Topics

Disease

66	Glaucoma 05/2022 - 09/2002
53	Open-Angle Glaucoma (Glaucoma, Open Angle) 11/2022 - 08/2003
12	Exfoliation Syndrome 01/2021 - 09/2010
7	Angle-Closure Glaucoma (Glaucoma, Angle Closure) 01/2020 - 01/2012
5	Cataract (Cataracts) 01/2020 - 01/2014
5	Optic Nerve Diseases (Optic Neuropathy) 01/2019 - 09/2008
5	Ocular Hypertension (Glaucoma, Suspect) 09/2017 - 04/2008
4	Low Tension Glaucoma 05/2020 - 08/2011
4	Type 2 Diabetes Mellitus (MODY) 10/2019 - 01/2013
4	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2019 - 12/2015
3	Diabetes Mellitus 03/2022 - 01/2014
3	Wounds and Injuries (Trauma) 01/2021 - 01/2014
3	Genetic Risk Score 01/2020 - 01/2017
3	Hypertension (High Blood Pressure) 12/2018 - 06/2011
2	Neurodegenerative Diseases (Neurodegenerative Disease) 05/2022 - 01/2022
2	Ganglion Cysts (Ganglion) 01/2022 - 01/2021
2	Genetic Predisposition to Disease (Genetic Predisposition) 01/2021 - 01/2017
2	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 06/2015
2	Neoplasms (Cancer) 01/2018 - 05/2012
2	Obesity 01/2017 - 05/2013
2	Atrophy 07/2008 - 04/2003
1	Immune System Diseases (Immune Disorders) 01/2021
1	Optic Nerve Injuries 01/2021
1	Retinal Arterial Macroaneurysm 01/2020
1	Retinal Vein Occlusion 01/2020
1	Refractive Errors (Refractive Error) 05/2019
1	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 01/2019
1	Weight Gain 01/2019
1	Hypercholesterolemia 01/2019
1	Body Weight (Weight, Body) 01/2019
1	Aneurysm (Aneurysms) 01/2019
1	Intracranial Aneurysm (Cerebral Aneurysm) 01/2019

Drug/Important Bio-Agent (IBA)

23	Retinaldehyde (Retinal)IBA 03/2022 - 12/2007
7	Hormones (Hormone)IBA 11/2022 - 10/2007
5	SteroidsIBA 03/2022 - 01/2014
5	Pharmaceutical PreparationsIBA 01/2021 - 10/2014
5	Estrogens (Estrogen)FDA Link 01/2016 - 08/2012
4	CholesterolIBA 01/2022 - 08/2016
4	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022 - 01/2019
4	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2014
4	Caffeine (No Doz)FDA LinkGeneric 01/2021 - 05/2008
4	Proteins (Proteins, Gene)FDA Link 01/2021 - 05/2013
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019 - 01/2016
3	Oral ContraceptivesIBA 11/2022 - 01/2016
3	Coffee FDA Link 01/2021 - 09/2012
3	Bupropion (Wellbutrin)FDA LinkGeneric 01/2020 - 01/2012
3	Synthetic Prostaglandins (Prostaglandin Analogues)IBA 01/2018 - 09/2002
3	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 01/2016 - 02/2010
3	Brimonidine Tartrate (Alphagan)FDA LinkGeneric 07/2014 - 08/2011
3	Nitric Oxide Synthase (NO Synthase)IBA 06/2011 - 02/2010
2	trabecular meshwork-induced glucocorticoid response proteinIBA 01/2020 - 01/2019
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 01/2015
2	SolutionsIBA 01/2019 - 02/2015
2	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2019 - 03/2013
2	Gonadal Steroid Hormones (Sex Hormones)IBA 10/2018 - 01/2018
2	ClusterinIBA 01/2018 - 10/2015
2	betaglycan (TGFBR3)IBA 01/2017 - 07/2015
2	Ophthalmic Solutions (Eye Drops)IBA 03/2016 - 05/2007
2	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 10/2014 - 10/2014
2	ElastinIBA 10/2014 - 09/2010
2	Soluble Guanylyl CyclaseIBA 04/2013 - 01/2013
2	ArgonIBA 07/2006 - 01/2005
1	Branched-Chain Amino AcidsIBA 05/2022
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 01/2021
1	Protein AggregatesIBA 01/2021
1	Ginkgo biloba extract (Rokan)IBA 05/2020
1	CannabinoidsIBA 01/2020
1	Dietary Carbohydrates (Carbohydrate, Dietary)IBA 01/2020
1	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 01/2020
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2020
1	Apolipoproteins E (ApoE)IBA 01/2020
1	Antidepressive Agents (Antidepressants)IBA 01/2020
1	Adrenergic Agonists (Adrenergic Receptor Agonist)IBA 01/2020
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2020
1	Metformin (Glucophage)FDA LinkGeneric 01/2020
1	Topiramate (Topamax)FDA LinkGeneric 01/2020
1	SulfonamidesIBA 01/2020
1	Cholinergic Antagonists (Anticholinergics)IBA 01/2020
1	Blood Glucose (Blood Sugar)IBA 10/2019
1	Contraceptive Agents (Contraceptives)IBA 05/2019
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2019
1	Carisoprodol (Soma)FDA LinkGeneric 01/2019
1	ImmunosorbentsIBA 01/2019
1	Phosphodiesterase 5 InhibitorsIBA 01/2019
1	Type I Tumor Necrosis Factor ReceptorsIBA 01/2019
1	Type II Tumor Necrosis Factor ReceptorsIBA 01/2019
1	Tadalafil (Cialis)FDA Link 01/2019
1	Pilocarpine (Ocusert)FDA LinkGeneric 01/2019
1	Edetic Acid (EDTA)FDA Link 01/2019
1	EnzymesIBA 01/2019

Therapy/Procedure

11	Trabeculectomy (Trabeculoplasty) 01/2022 - 09/2002
11	Lasers (Laser) 01/2022 - 09/2002
7	Therapeutics 11/2018 - 01/2008
2	Slit Lamp 01/2021 - 06/2014
2	Glaucoma Drainage Implants 10/2018 - 01/2007
2	Phacoemulsification 08/2017 - 01/2017
2	Filtering Surgery 01/2017 - 01/2015
2	Ovariectomy (Oophorectomy) 01/2016 - 04/2014
1	Carbohydrate-Restricted Diet (Low Carbohydrate Diet) 01/2020
1	Microspheres (Microsphere) 01/2019